Note: When you Easy Apply, please upload a pdf of your resume along with a cover letter (both in one document) that briefly describes your interest in the role and how you think you could contribute to the team. Resumes with no cover letters will NOT be reviewed.

Cell therapy is emerging as a paradigm-shifting strategy in healthcare. To harness this potential, stringent process controls must be put into place that monitor and measure critical parameters of the cell product at every step, from patient sample acquisition to drug product release. While traditional flow cytometers are the gold standard for cell analysis, they are not well suited for the manufacturing environment.

Accellix has developed a rapid, fully automated, sample to analysis, cell phenotyping platform, bringing a simple, standardized quality control solution to the cell therapy market. Currently serving global pharma and biotech companies, Accellix is well on the way to setting the standard for quality control in cell and gene therapy. See more information about the company on our website at https://www.accellix.com

The Accellix Assay Development team is looking to recruit talented individuals to help develop custom flow cytometry assays in partnership with many leading pharmaceutical companies, expand our catalog of off-the-shelf assay kits, and to support our software team to develop automated analysis algorithms. The candidate should bring to the table relevant experience, enthusiasm for having a tangible impact on cell therapy, and a collaborative and down-to-earth attitude.

Responsibilities

Develop and qualify flow cytometry assay panels on the Accellix platform, including optimization of formulations and protocols
Collaborate with cross-functional teams while following design and development plans, executing assay verification and validation, and ensuring all assay requirements are satisfied
Provide analysis and feedback for developing automated analysis software
Follow good manufacturing practices (GMP) in lab, clearly document experimental procedures and results, and assist team in maintaining inventory of lab supplies and reagents
Participate in drafting and editing protocols for assay kit manufacturing and QC, and in tech transfer of new assays to the manufacturing team
Present updates on projects and initiate brainstorming/troubleshooting discussions within the team and to external customer audiences
Promote a strong working relationship with others in the lab, facilitate open communication, proactively identify and address issues, and support other team members to meet deadlines and manage shifting priorities

Required Qualifications

Senior Research Associate: BS with 4+ years or MS with 2+ years, Associate Scientist: BS or MS with 8+ years, Scientist: PhD 0-2 years of relevant Industry experience
Experience with experimental design and execution of flow cytometry assays, including antibody titrations, and optimizing and troubleshooting multicolor assays
Experience with flow cytometry data analysis using FlowJo or similar analysis software
Demonstrated ability to manage multiple projects, meet goals in a timely fashion, communicate delays and escalate challenges immediately
Ability to design, execute, and analyze experiments with minimal oversight
Ability to communicate effectively and collaborate within and across teams

Desired Qualifications

Experience with generating and optimizing compensation matrices to address fluorescence spectral overlap in multiparametric flow data
Familiarity with common biomarkers found on leukocytes, and/or familiarity with cell-based therapies and cellular engineering
Experience with product development or instrument automation in an industry setting
Experience with assay transfer to internal or external collaborators
Experience with good documentation practices (GDP) and with drafting and reviewing documents such as SOPs and development reports

Does this sound like a good fit for you? If so, we would love to hear from you. Please upload a pdf of your resume along with a cover letter that briefly describes your interest in the role and how you think you could contribute to the team!

Accellix

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Senior Research Associate/Associate Scientist/Scientist, Assay Development