The Coriell Institute for Medical Research is seeking an ambitious and highly skilled Research Technician III to play a critical leadership role within our Research and Development (R&D) team. This position is integral to advancing Coriell’s mission to innovate in the areas of stem cell research, genome editing, and supporting the Camden Cancer Research Center (CCRC) biobank.
In addition to contributing to cutting-edge research, you will oversee the day-to-day laboratory activities, ensuring smooth operations, mentoring research technicians, and promoting a culture of collaboration and scientific rigor. This role demands a combination of strong leadership, laboratory management, independent problem-solving, and teamwork to maintain high productivity and precision in the lab.
As a key member of the R&D team, you will collaborate with top scientists and researchers, playing a direct role in generating induced pluripotent stem cell (iPSC) lines, differentiated cellular models, organoids, and isogenic controls using CRISPR-Cas9 technology. You will also support and manage activities that ensure quality control.
Key Responsibilities:
- Leadership & Oversight: Lead and support research technicians by overseeing day-to-day laboratory activities, mentoring team members, and ensuring adherence to safety and quality protocols.
- iPSC Reprogramming: Reprogram primary human cell lines into iPSCs, ensuring adherence to best practices and high-quality standards.
- Cell Line Management: Perform routine maintenance, expansion, and cryopreservation of various human cell lines. This includes documenting cell culture processes and ensuring traceability.
- Characterization & Quality Control: Utilize a range of techniques (such as immunohistochemistry, flow cytometry, and qPCR) to characterize iPSC and differentiated cell lines, ensuring consistency and reproducibility in experimental data.
- Flow Cytometry: Plan, execute, and analyze flow cytometry experiments to characterize cell surface markers and evaluate the quality and purity of iPSCs and differentiated cell types. Ensure accurate data analysis and interpretation to support ongoing R&D efforts.
- CRISPR-Cas9 Genome Editing: Execute precise CRISPR-Cas9 protocols for genome modification, contributing to the creation of isogenic cell lines.
- Laboratory Recordkeeping: Maintain detailed, accurate, and up-to-date laboratory records, ensuring all data are traceable and can be used in future projects and publications.
- Inventory & Reagent Management: Oversee the maintenance and organization of lab inventories, reagents, media, and various instruments. Ensure all laboratory functions run smoothly by assisting in routine equipment maintenance and compliance with safety standards.
- Cross-Team Collaboration: Work closely with other members of the R&D team and other departments within the institute to share insights and develop best practices in cell biology and molecular genetics.
- Continuous Learning: Stay up to date with advancements in stem cell technologies, genome editing, flow cytometry techniques, and related fields to enhance your contributions to the R&D team.
- Continuous Learning: Stay at the forefront of developments in stem cell technology, genome editing, biobanking practices, and related fields, applying new knowledge to enhance ongoing R&D and biobank efforts.
Qualifications:
- Master’s or Ph.D. degree in Cell/Molecular Biology, Biotechnology, or a related field.
- Minimum of 5 years of hands-on experience with iPSCs and human cell lines.
- Proficiency in aseptic cell culture techniques and ability to troubleshoot and optimize protocols.
- Expertise in molecular and cell biology techniques, including ELISA, qPCR, DNA/RNA isolation, immunohistochemistry, and flow cytometry.
- Strong working knowledge of CRISPR-Cas9 genome editing with proven ability to validate and troubleshoot experiments.
- Experience or familiarity with biobanking practices and cellular quality control standards.
- Proven leadership and laboratory management experience, with the ability to mentor and guide research technicians.
- Exceptional attention to detail, analytical skills, and ability to manage multiple projects in a dynamic research environment.
- Meticulous recordkeeping and organizational skills, with a commitment to maintaining laboratory and biobank best practices.
- Excellent communication skills and ability to work collaboratively within interdisciplinary teams.
Preferred Skills:
- Experience working within non-profit, medical, or academic research settings.
- Knowledge of biobanking practices.
- Experience in handling high-throughput data, contributing to publications, or presenting at scientific conferences.
Coriell & Recruitment
Founded in 1953, the Coriell Institute for Medical Research is a nonprofit research institute dedicated to improving human health through biomedical research. Coriell scientists lead research in personalized medicine, cancer biology, epigenetics, and the genomics of opioid use disorder. Coriell also hosts one of the world's leading biobanks—comprised of collections for the National Institutes of Health, disease foundations and private clients—and distributes biological samples and offers research and biobanking services to scientists around the globe. To facilitate drug discovery and disease study, the Institute also develops and distributes collections of induced pluripotent stem cells. To learn more, visit www.coriell.org.
Any offer of employment extended by Coriell is contingent on an applicant’s ability to be Authorized to Work in the United States of America. Upon date of hire, all employees are required to provide whichever valid Employment Authorization Documents they wish, as long as it is in compliance with Federal Regulations.
This job description/posting is to provide general guidance on the nature of work that will be performed in this position. It is not represented to be a full or exhaustive list of the duties, responsibilities, or qualifications needed for this role. Due to the nature of our work, the duties, responsibilities, and qualifications listed on this job description/posting are subject to change.
Coriell is an Equal Opportunity Employer, who values a diverse work environment, who is committed to providing reasonable accommodations to individuals with disabilities. Coriell is an at-will employer.
