R&D Partners is seeking to hire an Senior Research Associate, Formulations in South San Francisco, CA.
We are excited to welcome a passionate and skilled individual to join our Analytical and Formulation Sciences team within the Drug Discovery Department. This lab-based position offers a unique opportunity for you to expand your expertise in formulation and analytical sciences while contributing to the discovery of novel medicines. As a member of research project teams, you will conduct activities related to test article formulation to support drug discovery programs driving advancements in biological target pharmacology, small molecule lead optimization and development candidate selection.
Your main responsibilities as a Senior Research Associate, Formulations:
- Execute experiments for the formulation and QC of oral and parenteral vehicles for in vivo evaluation of novel lead materials.
- Prepare and deliver accurate formulation of test articles to achieve experimental goals. Conduct solid form characterization including thermodynamic solubility, particle size, polyform characterization, melting point, salt equivalent determination, and water content analysis to advance lead compounds toward candidate nomination.
- Work closely with experts in medicinal chemistry, DMPK, pharmacology, and technical operations to generate key data that drive understanding of ADMET properties and test article pharmacology.
- Partner with Technical Operations and CMC teams to develop prototype formulations and processes for non-GLP pre-clinical studies in advanced research programs.
- Operate state-of-the art analytical instruments, such as Agilent HPLC 1260, waters LCMS, PLM, and Rigaku Miniflex XRPD.
- Track formulation activities under tight timelines, ensuring cross-functional collaboration and accountability.
What we are looking for in a Senior Research Associate, Formulations:
- Master's with 2+ years, or Bachelor’s with 5+ years of relevant experience in an academic, biotech, or pharmaceutical industry
- Degree in Pharmaceutics, Pharmaceutical Sciences, Chemistry, Analytical Chemistry, Biochemistry, Chemical Engineering, or related discipline
- Proven experience in developing and optimizing oral and/or parenteral, formulations of small molecules for the characterization of ADMET properties or in vivo pharmacology
- Hands on experience with HPLC analysis, stability testing, and physicochemical property determination. Familiarity with solid form characterization techniques, including PLM, TGA, DSC, XRPD, and Dissolution preferred.
- Strong experimental design skills for various dose formulations, along with expertise in developing methods for drug materials with low solubility.
Pay Scale:
$100,000 - $122,000 annually
R&D Partners is a global functional service provider and strategic staffing resource specializing in scientific, clinical research & engineering. We provide job opportunities within major pharmaceutical, biopharmaceutical, biotechnology, and medical device companies.
R&D Partners is an equal-opportunity employer.
