Senior Associate Scientist - In Vitro Pharmacology / HTS

Our Cambridge-based client is a dynamic and innovative biotechnology startup positioned in the vibrant Boston/Cambridge biotech hub. Their cutting-edge platform leverages synergistic mechanisms in human biology to develop groundbreaking therapeutics for diseases with significant unmet needs. They seek to grow the team and are looking for an experienced IVP specialist with a solid foundation in HTS, Hit-to-Lead & Target Validation.

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Responsibilities

Develop, validate, and execute binding, biochemical, and cell-based assays to characterize small molecule inhibitors of novel targets
Analyze assay results, normalize to controls, upload screening data into a central database, and highlight key findings
Collaborate with a multi-disciplinary team, presenting key findings at regular lab and team meetings
Help manage inventory of biological reagents, cell lines, and small molecule libraries using a LIMS
Maintain accurate, well-organized experimental records in an electronic lab notebook

Required Qualifications

BS in a relevant scientific area with 5+ years in biotech or pharma, with significant direct experience in in vitro pharmacology assay development/execution to elucidate small molecule SAR and MOA
Expertise in aseptic techniques and mammalian tissue culture, growing various mammalian cell lines, and knowledge of best practices for maintaining and QC of cell stocks.
Target ID & Validation experience
Experience developing and running various medium to high-throughput assays for mechanism of action or SAR, curve fitting, and uploading data to a centralized database (e.g., CDD Vault, Dotmatics)
Highly motivated, eager to drive research forward based on broad objectives and vision
Ability to adapt to evolving priorities in a fast-paced research environment, with a passion for continuous learning

Birdseye Partners

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